Successful treatment of facial vitiligo with honey bee, Allium cepa and Avena sativa combined to sun light exposure: A case clinical trial

Objectives: To evaluate efficacy and safety of a natural formulation, completed by sun light exposure, in the management of localized vitiligo. Case summary: A 34 –yearold man was affected by facial localized vitiligo with no family history of this disease. After 17 months of treatment with conventional drugs with unsatisfactory results, the patient has adopted a new therapeutic protocol including topical application of a formulation of honey bee, Allium cepa L. juice and Avena sativa L. stem decoction. Also, a daily sun light exposure of 15-20mn was practiced. Results and discussion: A complete re-pigmentation of white patches was obtained in a period of 11 months with no adverse effects. The prolactin value was 7.06 ng/ml and cortisol was 12.36 μg/dl with 17.14 g/l of sericIgG which reflect a stabilization of stress state of the patient. Conclusions: The tested complementary therapy was safe and has successfully re-pigmented the different vitiligo lesions. Further studies are needed to confirm this stimulation of melanocyte’s proliferative activity by the present formulation.